- Potentiated metastasis of TSCC via miR-140-5p/PAK1 axis modulation; - Modulated TSCC metastasis partially through the regulation of SPRR; - Mediated the pro-metastatic role of STAT3 in HNSCC via interaction with miR-30a; - Promoted OSCC metastasis by inducing EMT. This evidence concerns the gene PAK1 and head and neck squamous cell carcinoma.