CRP and cardiovascular disorder: Several clinical studies have shown a strong and independent relationship between higher values of CRP and poor prognosis in cases with cardiovascular disease.14,15 In addition to its role in prognosis, Wasser et al found thatsome inflammatory markers, including CRP, play a pivotal role in the occurrence of ISR in subjects who underwent carotid artery stenting.16 Moreover, Stone et al showed that preprocedural high sensitivity-CRP values were associated with major adverse limb events in which receiving interventions distal to the iliac arteries.17