The CAR has been extensively investigated in patients with several types of malignancies in previous studies.20-22 This new index has also gained attention in cardiovascular disease because studies reported that a combination of these parameters into a single index is a more sensitive parameter in predicting inflammation than CRP or albumin alone due to opposite directions of each marker.14,23,24 In addition, it can be hypothesized that as a single inflammatory index, the CAR may provide stability against serum CRP and albumin alone. This evidence concerns the gene CRP and cardiovascular disorder.