NOS2 and Parkinson disease: According to Table 2, treating a rotenone-induced mouse model of PD with CAPE (2.5-10 mg/kg/every other d/17 days) inhibited microglial activation (CD11b+); downregulated the activity of NF-κB, iNOS, and cyclooxygenase-2 (COX-2); and reduced the production of TNF-α and IL-1β.