the result showed that UBE2C (Figure 4A), CDC20 (Figure 4B), BIRC5 (Figure 4C), TK1 (Figure 4D), TACC3 (Figure 4E), CXCR4 (Figure 4F) and SDC1 (Figure 4G) were upregulated in ovarian cancer compared with normal group (all P<0.05), and there were no significant differences in the expression of RNASEH2A, RNASEH2B and RNASEH2C between ovarian cancer samples and normal samples (Supplementary Figure S1A-C). The gene discussed is TK1; the disease is ovarian cancer.