TK1 and ovarian carcinoma: After validation of gene expression and evaluation of prognostic values of hub genes, only high expression of UBE2C (P=0.045, HR=1.15 [1-1.32], Figure 5A), TK1 (P=0.044, HR=1.25 [1.01-1.54], Figure 5D), TACC3 (P=0.0054, HR=1.23 [1.06-1.43], Figure 5E) and CXCR4 (P=0.022, HR=1.17 [1.02-1.34], Figure 5F) were significantly correlated with poor PFS of patients with ovarian cancer.