Wang Y et al 32 evaluated expression variation of MALAT1 after treated with TGF-β, finding that TGF-β significantly induced malat1 levels in human head and neck squamous cell carcinoma cells; subsequent similar work by Du MY et al 33 detected MALAT1 expression variation in 6-10B cells treated with TGF-β by way of qRT-PCR, showing that TGF-β treatment increased MALAT1 expression in nasopharyngeal carcinoma. This evidence concerns the gene MALAT1 and head and neck squamous cell carcinoma.