The results showed a cis-eQTL correlation between the SNP rs1010208 genotype and the expression of HINT1, thereby, indicating that the target gene of SNP rs1010208 is HINT1. Nonetheless, no cis-eQTL correlation was detected between the SNP rs1010208 genotype and the expression of CDC42SE2. Thus, we observed that the expression of HINT1 and CDC42SE2 mRNA in cancer tissues was lower than that in the adjacent tissues (P-value < 0.001, Supplementary Figure S3). The gene discussed is CDC42SE2; the disease is cancer.