TNF and Thrombocytopenia: During IC, no statistically significant difference was found in the incidence of grade 3/4 thrombocytopenia between the two groups (P = 1.000), but the frequency of grade 3/4 thrombocytopenia in the TNF + N group during CCRT (15.9%, 18/113) was significantly different than that in the TPF + P group (5.3%, 6/113) (P = 0.010).