GZMK and hepatocellular carcinoma: TCR repertoire overlap between a terminally exhausted TIL population, characterized by high expression of coinhibitory receptor genes, and a predysfunctional TIL population, characterized by expression of GZMK, was also found in human melanoma (64), NSCLC (60), colorectal cancer (CRC) (80) and hepatocellular carcinoma (HCC) (65).