IL6 and COVID-19: Whilst more studies are required, emerging data implies a role for IL-6 in driving the SARS-CoV-2-mediated remodeling of the monocyte pool (117, 118), with one group demonstrating a significant reduction in the expression of genes involved in “leukocyte chemotaxis” and the “acute inflammatory response” in monocytes obtained from COVID-19 patients following treatment with the IL-6 receptor monoclonal antibody Tocilizumab (117).