IgG–aPL was associated with cardiopulmonary involved [OR 30.512 (95% CI 1.969–472.780), P=0.015], acute coronary syndrome [OR 0.025 (0.001–0.906), P=0.025], pulmonary embolism [OR 0.058 (0.004–0.906), P=0.042] and thrombocytopenia [OR 1.992 (1.024–3.872), P=0.042]. The gene discussed is FASLG; the disease is Thrombocytopenia.