At the same time, we found that compared with those without ASXL1 mutation, those with ASXL1 mutation had a higher mutation load of U2AF1 (p = 0.674), and the proportion of bone marrow blasts was higher (p = 0.145), which was more distributed in patients with MDS-EB (p = 0.092). This evidence concerns the gene ASXL1 and myelodysplastic syndrome.