Treatment of NSCLC cells with chloropyramine increased SASH1 protein expression (Fig. 4A) and a significant decrease in cell survival at 25 μM for the HCC827, H-226 and H1299 cell lines and at 50 μM for all other NSCLC cell lines, with the exception of A549 cells (Fig. 4B–G). The gene discussed is SASH1; the disease is non-small cell lung carcinoma.