In our cohort of 117 consecutive unresectable NSCLC patients in stage III treated with chemoradiotherapy PD-L1 expression from biopsy samples taken before therapy had no prognostic value regarding PFS and OS, neither comparing the groups of patients with more or less than 1% PD-L1 expression or groups with more or less than 50%. Here, CD274 is linked to non-small cell lung carcinoma.