Specifically, miR-193b regulates ALDH3A2 and let-7b interacts with ALDH7A1 in obesity, however, in liver cancer, miR-193b regulates ALDH7A1 and let-7b targets HADHA, they regulate different genes (miR-193b /ALDH7A1, let-7b/HADHA) that participate in the same functional process. This evidence concerns the gene HADHA and obesity disorder.