PRNT and cancer: M8 was effective in inducing an IFN-dependent intrinsic cell death, characterised by the expression of markers of ICD-related DAMPs, as well as immune response in different cancer cell types including metastatic melanoma Mel1007 and Mel120, lung adenocarcinoma A549, colon carcinoma HCT116, and prostate carcinoma PC3 [51].