Aiming to compare continuous subcutaneous insulin infusion and multiple daily insulin injections, Jeitler et al. [26] made a systematic review and meta-analysis comparing the effects of continuous subcutaneous insulin infusion, with multiple daily insulin injections, on glycemic control, risk of hypoglycemic episodes, insulin requirements, and adverse events, in type 1 and type 2 diabetes mellitus patients. The gene discussed is INS; the disease is type 2 diabetes mellitus.