The increased expression of PMP70, ACBD5, CAT, PEX5, PEX19, PECI, ACOX1, ACOX3, SCPx, and ABCD1 in 22Rv1 cells, compared to nontumor cells, suggests that PCa take advantage of the peroxisomal lipid metabolism, upregulating the import of fatty acids (via PMP70, ABCD1, and ACBD5), and the classical peroxisome proliferator-inducible and noninducible pathways (via ACOX1 and ACOX3, respectively). Here, ECI2 is linked to posterior cortical atrophy.