PEX5 and neoplasm: In later tumor stages, here represented by PC3 cells, the expression levels of peroxisomal PMP70, ACBD5, CAT, PEX5, and PEX19 decrease if compared to 22Rv1 cells, suggesting that their respective pathways may become less relevant with disease progression, in accordance with the switch to the Warburg effect that is observed at this stage [34].