The myopathy is characterized by symmetric muscle weakness, markedly elevated serum creatine kinase (CK) levels, abnormal electromyography (EMG) [9], and histologic evidence of muscle cell necrosis and degeneration, along with a lack of significant inflammatory infiltrates and circulating autoantibodies against 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) [7,10], which have been recognized as possible pathogenic autoantibodies [10,11]. This evidence concerns the gene HMGCR and myopathy.