“If it is still known that angiotensin-converting enzyme 2 (ACE2) receptors [37,38] are also found in different niches along the digestive tract, why is the number of studies that aim to identify SARS-CoV-2 using rectal swabs or stool samples limited?” In several previous occasions, it has been demonstrated the presence of viral signatures in stool samples starting from day seven, and ranging up to almost two weeks after infection [39,40,41,42]. The gene discussed is ACE2; the disease is infection.