FLT1 and malignant colon neoplasm: VEGFR1 has been detected in a series of colon cancer cell lines (i.e., HT29, SW480, SW620, ATCC, KM12 L4, KM12 SMLM2, GEO, RKO) [67], with evidence suggesting that the receptor is involved in processes that promote tumor progression and metastasis [66,67].