GPX3 and cardiovascular disorder: Although numerous human studies have shown consistent effects of beer and other beverages on several intermediate markers for cardiovascular diseases [9,19,22,23,24], it is still unknown whether their action could be specifically related to polyphenols and especially to main human proteins (human serum albumin (HSA), plasma circulation fibrinogen (PCF), C-reactive protein (CRP), glutathione peroxidase 3 (GPX3)), which are relatively new biomarkers of coronary artery disease (CAD).