MMP3 and rheumatoid arthritis: Studies have shown that RA can be treated by triple therapy (MTX + anisulfapyridine + hydroxychloroquine) or MTX plus infliximab therapy.[9] Nowadays, there may be more options in clinical practice because western medicine simple therapy is not completely risk-free, for example, the choice of traditional Chinese medicine preparations combined with MTX to inhibit MMP-3 levels may be an effective regimen with a protective effect on the patient's bone and joint.