Since these genes are both members of the RTK family of cell surface receptors that play an important role in the regulation of cell proliferation, metabolism and survival [12] and tumours identified to be EGFR amplified have shown to be more invasive [6, 15], it is reasonable to consider that amplification of these genes may drive the growth of tumours through increasing the intrinsic proliferative and invasive abilities of these cell sub-populations. Here, CD177 is linked to neoplasm.