BRCA1 and Hereditary breast and ovarian cancer syndrome: The Centers for Disease Control and Prevention lists testing for HBOC syndrome as a tier 1 genomic application, with “significant potential for positive impact on public health based on available evidence-based guidelines and recommendations,”9 but, to date, the US Preventive Services Task Force guidelines for BRCA1/2 testing recommend against routine risk assessment, genetic counseling, or genetic testing for women whose personal or family history does not suggest HBOC carrier status.10