After removing the CD4:CD8 ratio, RNA:DNA ratio remained significantly associated with decreased carotid IMT progression for tertile 2 vs 1 (−0.032 [95% CI, −0.063 to −0.001] mm/y; P = .045) and tertile 3 vs 1 (−0.032 [95% CI, −0.063 to −0.001]; P = .04) (eTables 1 and 2 in the Supplement), but the other models did not change significantly. Here, CD4 is linked to inflammatory myofibroblastic tumor.