Current data demonstrate that treatment of hyperglycemia with insulin during CABG surgery can lead to postoperative hypoglycemia[7,8] and does not always prevent hyperglycemia[9], especially when selecting a tight blood glucose target, such as 80-110 mg/dl (4.4-6.1 mmol/l)[3,4,7,10-12]. Here, INS is linked to Hypoglycemia.