APOE and atherosclerosis: Lastly, in order to better understand atherosclerosis, which is a chronic inflammatory vascular disease related to high risk of myocardial infarction and cerebrovascular events, use of ApoE-/-, 64Cu-NP (LyP-1) 4-dendrimer-BAT (BAT((p-(bromoacetamido)benzyl)-1,4,8,11-tetraazacyclotetradecane-N,N′′,N′′′,N′′′′-tetraacetic acid) in mice showed high uptake in the aortic root and descending aorta by PET/CT (Delgado et al., 2000; Subramanian et al., 2010; Criscione et al., 2011; Liu et al., 2011; Seo et al., 2014; Woodard et al., 2016).