In a separate study, Buescher and Hair reported that HM of mothers with mastitis had the same anti-inflammatory components and characteristics of HM from healthy mothers; although elevation in selected components/activities was observed (TNFα, soluble TNF receptor II, and IL-1RA and bioactivities that cause shedding of soluble TNF receptor I from human polymorphonuclear neutrophils) (120). The gene discussed is TNF; the disease is mastitis.