They proposed that the intrinsic FASN of tumor cells promotes the development of ovarian cancer by weakening anti-tumor immunity, and found that the activation of FASN in cancer cells can lead to an increase in lipid concentration in TME, and the accumulation of abnormal lipids inhibits the ability of tumor infiltration DC (TIDC) to support anti-tumor T cells. The gene discussed is FASN; the disease is ovarian carcinoma.