We found that MASTL depletion decreased c-Myc protein levels (Figure 6C), and that PP2A-B55α depletion more strongly decreased both serine 62-phosphorylation of c-Myc and total c-Myc compared with PP2A-B55δ and PP2A-B56α in MCF7 cells (Figure 6D), suggesting that MASTL may regulate c-Myc via PP2A-B55α in breast cancer cells. Here, MYC is linked to breast cancer.