The expression of E-cadherin was upregulated, while that of zinc finger E-box-binding homeobox 1 (ZEB1), Snail, and Fibronectin was downregulated in lncRNA NR_027471-overexpressing osteosarcoma cells compared to pLVX-Vector group (Figure 3D). The gene discussed is ZEB1; the disease is osteosarcoma.