To explore the correlation of PKM2 expression with the clinical outcome of prostate cancer patients, immunohistochemical analysis showed that the level of PKM2 expression was elevated in prostate cancer tissues compared with normal tissues (Figure 1A), which is in line with mRNA analysis of PKM2 from the ONCOMINE microarray gene expression dataset2 and clinical sample (Figure 1B). This evidence concerns the gene PKM and prostate cancer.