A meta-analysis of 62 randomized controlled trials involving 34 941 patients quantified the effect of any of the SGLT2 inhibitors (empagliflozin, canagliflozin, dapagliflozin, tofogliflozin, licogliflozin, or ipragliflozin) on reducing SUA levels in patients with T2DM [27]. Here, SLC5A2 is linked to type 2 diabetes mellitus.