This idea gains further momentum from the fact that epoxy-PUFA [as well as the anti-inflammatory cytokine IL-10 (36)] are at significantly lower levels in amniotic fluid of patients in clinical chorioamnionitis without microbial infection (regardless of intra-amniotic inflammatory cytokine, IL-6, levels) compared to those in normal spontaneous labor (48). The gene discussed is IL10; the disease is chorioamnionitis.