◾Decreases pro-inflammatory cytokines, TNF-α and IFN-γ and increases anti-inflammatory IL-10 production. ◾Reduces the duration and severity of upper respiratory infections (viral infections). ◾Scavenges ROS, prevents lipid peroxidation, and protein alkylation and thus protect cells from oxidative stress induced cellular damage. The gene discussed is TNF; the disease is respiratory tract infectious disorder.