The PPARδ agonist GW0742 protects against angiotensin II (AngII)-accelerated atherosclerosis by inducing the expression of the Bcl6, and the regulators of G protein-coupled signaling (RGS) proteins RGS4 and RGS5, which in turn inhibit the expression of pro-inflammatory and atherogenic genes (77). Here, AGT is linked to atherosclerosis.