Apart from removing the pathogen, neutrophils release an array of inflammatory mediators such as serine proteases (38, 39), elastases, cathepsin G (39), nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (40), myeloperoxidases (MPO) (41), and matrix metalloproteases (37) essential to control localized infection but can also facilitate tissue damage (42). This evidence concerns the gene MPO and infection.