Even in peritoneal fluids of the naïve C57BL/6 mice, leptin increased CCL5 levels (from 8.3 ± 0.1 to 15.5 ± 2.6 pg/ml in control and leptin-stimulated C57BL/6 mice; respectively; mean ± SEM of at least five animals per group; + p < 0.05 compared to control group) and TNFα (8) preceding the minor eosinophilia triggered by leptin in these animals. The gene discussed is LEP; the disease is Increased total eosinophil count.