To explore the relationship between ISG12 expression with breast cancer tumorigenesis, we made use of the Breast Cancer Gene-Expression Miner database (http://bcgenex.centregauducheau.fr/BC-GEM/GEM-Accueil.php?js=1) to compare the ISG12 mRNA levels in tumors, adjacent-tumor tissue and normal tissue in breast cancer patients. The gene discussed is IFI27; the disease is breast cancer.