The conveyed effect depends on the “sponged” miRNA: while HRCR has an attenuating effect on hypertrophy by sponging miR-223 (Wang et al., 2016), CDR1as seems to amplify post-myocardial infarction (MI) ischemic damage in mice through sponging miR-7 (Geng et al., 2016). This evidence concerns the gene LINC00632 and myocardial infarction.