IL6 and systemic lupus erythematosus: For example, beta-sitosterol (LCW5), a common component of 10 herbs such as CS, DH, DG, HH, JYH, LQ, TR, XS, ZBM, and PGY, shows an inhibitory effect on the expression of proinflammatory cytokine interleukin IL-6 and TNF-α, which display the properties of anti-inflammatory and immune-modulating in the treatment of SLE (Fraile et al., 2012).