We established a new glioma classification model based on histochemistry and BMP2 expression (HB classification: HBs: rO, rAO, rOA; HBh: O, AO, OA; HBm: AOA, rAOA, A, rA, AA, rAA; HBl: GBM, rGBM), which is related to the prognosis of patients. The gene discussed is BMP2; the disease is central nervous system cancer.