Further recent study in the Brazilian population, showed that, the HMOX1 rs2071746 genotype frequencies were 24.3% (AA), 48.6% (AT) and 27.0% (TT) in the SCA patient group and 28.2% (AA), 52.7% (AT), 19.1% (TT) in the control group. This evidence concerns the gene HMOX1 and autosomal dominant cerebellar ataxia.