To understand the underlying mechanism by which YAP/TAZ modulate adipocyte survival during obesity, we performed expression profiling by RNA sequencing (RNA-seq) and quantitative RT-PCR using total RNA isolated from white adipocytes of Ad-Yap/Taz-KO mice and of wild-type littermates, which had been fed HFD for 4 weeks. The gene discussed is YAP1; the disease is obesity due to melanocortin 4 receptor deficiency.