To examine the effect of FOXP3 on the proliferation and migration of HCC cells, we first selected two cell lines with low FOXP3 expression, Hep3B and PLC/PRF/5 (Supplementary Fig. S3C), and generated FOXP3-overexpressing stable Hep3B and PLC/PRF/5 cell. The gene discussed is FOXP3; the disease is hepatocellular carcinoma.