FOXP3 and neoplasm: The IHC staining showed that the expression of FOXP3 and FOXP3Δ3 was positive in both hepatocytes and infiltrated lymphocytes (Fig. 1a, c), and the immune reactive score results indicated that the expression of FOXP3 was significantly higher in the hepatocytes of the adjacent normal tissues than the tumor tissues (Fig. 1b), whereas for FOXP3Δ3, there was no significant difference between the adjacent normal tissues and tumor tissues (Fig. 1d).