MASP2 and atypical hemolytic-uremic syndrome: Of note, an inhibitory antibody against MASP-2 (Narsoplimab) is currently undergoing phase 3 clinical trials for the treatment of Hematopoietic Stem Cell Transplant-Associated TMA (ClinicalTrials.gov Identifier: NCT04247906), IgA Nephropathy (NCT03608033) and Atypical Hemolytic Uremic Syndrome (NCT03205995) and in a phase 2 clinical trial for the treatment of Lupus Nephritis (NCT02682407), thus making the present work potentially transferable to the clinical setting in the near future.