A proof of this physiological response is given in the results shown in Figure 5: DFP-induced iron deficiency is sensed at the cellular level, where a correlation for an increase in iron cellular uptake receptor (TfR) and a decreased level of storage and efflux of cellular iron receptors (ferH and ireg1) was observed in the head kidneys of trout. The gene discussed is SLC40A1; the disease is Iron deficiency anemia.