Diagnostic scores were identified as follows: logit (P = HCC) = − 13.9106 + (1.3676 × ABCB6 expression level) + (− 0.1018 × FLVCR1 expression level) + (− 0.2817 × SLC48A1 expression level) + (1.1909 × SLC7A11 expression level). The gene discussed is SLC7A11; the disease is hepatocellular carcinoma.