GDF15 and coronary artery disorder: There was a two-sample MR study based on GWAS that indicated GDF-15 levels uncorrelated to risk of cardiometabolic outcomes [11], including body mass index, waist-hip ratio, waist circumference, whole-body lean mass, fat percentage, fasting glucose, glycated hemoglobin, fasting insulin, low density lipoprotein (LDL)-cholesterol, low density lipoprotein (HDL)-cholesterol, total cholesterol, triglycerides, type 2 diabetes, and CAD.