Other studies have reported associations between blood-group types and disease severity and multi-organ dysfunction in COVID-19.294,295 In the first publications of the COVID Human Genetic Effort, researchers found that 101 of 987 patients with life-threatening COVID-19 pneumonia had neutralizing immunoglobulin G auto antibodies against the interferons (IFNs), including IFN-ω and 13 types of IFN-α or both, at the onset of critical disease. The gene discussed is IFNA1; the disease is COVID-19.